SidaGhanaV1, Main, Exploration, bibRecord, 000C26

Changes in Sexual Risk Behavior Among Participants in a PrEP HIV Prevention Trial

Identifieur interne : 000C26 ( Main/Exploration ); précédent : 000C25; suivant : 000C27

Changes in Sexual Risk Behavior Among Participants in a PrEP HIV Prevention Trial

Auteurs : Greg Guest [États-Unis] ; Dominick Shattuck [États-Unis] ; Laura Johnson [États-Unis] ; Betty Akumatey [Ghana] ; Edith Essie Kekawo Clarke [Ghana] ; Pai-Lien Chen [États-Unis] ; Kathleen M. Macqueen [États-Unis]

Source :

Sexually transmitted diseases [ 0148-5717 ] ; 2008.

RBID : Pascal:09-0059294

Descripteurs français

Pascal (Inist)
- SIDA, Maladie sexuellement transmissible, Comportement sexuel, Prévention, Essai clinique.
Wicri :
- topic : Maladie sexuellement transmissible.

English descriptors

KwdEn :
- AIDS, Clinical trial, Prevention, Sexual behavior, Sexually transmitted disease.

Abstract

Background: One of the concerns raised regarding the introduction of any new HIV-prevention measure, such as PrEP, is the potential for risk disinhibition or sexual risk compensation. The oral tenofovir HIV prevention trial has been the subject of international discussion in this regard. Methods: This article maps the changes in sexual risk behavior among women participating in the oral tenofovir HIV prevention trial in Ghana. Content-driven, thematic analysis was carried out on qualitative data obtained from in-depth interviews with study participants. Growth curve analysis was the primary method used to document trends over time in self-reported sexual behavior collected monthly. Results: Overall, the study found that sexual risk behavior did not increase during the trial. Number of sexual partners and rate of unprotected sex acts decreased across the 12-month period of study enrollment. Certain subgroups of women, however, exhibited different growth curves. Data indicate that the HIV prevention counseling associated with the trial was effective. Conclusions: Counseling during the trial was effective. Different types of counseling and messaging may be needed for different subgroups within a population. These findings also have implications for required sample sizes for future HIV prevention trials where seroconversion is the main outcome.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000060
to stream PascalFrancis, to step Curation: 000077
to stream PascalFrancis, to step Checkpoint: 000063
to stream Main, to step Merge: 000C50
to stream Main, to step Curation: 000C26

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Changes in Sexual Risk Behavior Among Participants in a PrEP HIV Prevention Trial</title>
<author><name sortKey="Guest, Greg" sort="Guest, Greg" uniqKey="Guest G" first="Greg" last="Guest">Greg Guest</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Division of Behavioral and Biomedical Research, Family Health International</s1>
<s2>North Carolina</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Shattuck, Dominick" sort="Shattuck, Dominick" uniqKey="Shattuck D" first="Dominick" last="Shattuck">Dominick Shattuck</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Division of Behavioral and Biomedical Research, Family Health International</s1>
<s2>North Carolina</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Johnson, Laura" sort="Johnson, Laura" uniqKey="Johnson L" first="Laura" last="Johnson">Laura Johnson</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Division of Behavioral and Biomedical Research, Family Health International</s1>
<s2>North Carolina</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Akumatey, Betty" sort="Akumatey, Betty" uniqKey="Akumatey B" first="Betty" last="Akumatey">Betty Akumatey</name>
<affiliation wicri:level="4"><inist:fA14 i1="02"><s1>Department of Sociology, University of Ghana</s1>
<s2>Legon</s2>
<s3>GHA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Ghana</country>
<placeName><settlement type="city">Accra</settlement>
<settlement type="town">Legon (Ghana)</settlement>
<region type="region">Région du Grand Accra</region>
</placeName>
<orgName type="university">Université du Ghana</orgName>
</affiliation>
</author>
<author><name sortKey="Kekawo Clarke, Edith Essie" sort="Kekawo Clarke, Edith Essie" uniqKey="Kekawo Clarke E" first="Edith Essie" last="Kekawo Clarke">Edith Essie Kekawo Clarke</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Ghana Health Service, Ministry of Health</s1>
<s3>GHA</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Ghana</country>
<wicri:noRegion>Ghana Health Service, Ministry of Health</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chen, Pai Lien" sort="Chen, Pai Lien" uniqKey="Chen P" first="Pai-Lien" last="Chen">Pai-Lien Chen</name>
<affiliation wicri:level="2"><inist:fA14 i1="04"><s1>Division of Biostatistics, Family Health International</s1>
<s2>North Carolina</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Macqueen, Kathleen M" sort="Macqueen, Kathleen M" uniqKey="Macqueen K" first="Kathleen M." last="Macqueen">Kathleen M. Macqueen</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Division of Behavioral and Biomedical Research, Family Health International</s1>
<s2>North Carolina</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">09-0059294</idno>
<date when="2008">2008</date>
<idno type="stanalyst">PASCAL 09-0059294 INIST</idno>
<idno type="RBID">Pascal:09-0059294</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000060</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000077</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000063</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000063</idno>
<idno type="wicri:doubleKey">0148-5717:2008:Guest G:changes:in:sexual</idno>
<idno type="wicri:Area/Main/Merge">000C50</idno>
<idno type="wicri:Area/Main/Curation">000C26</idno>
<idno type="wicri:Area/Main/Exploration">000C26</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Changes in Sexual Risk Behavior Among Participants in a PrEP HIV Prevention Trial</title>
<author><name sortKey="Guest, Greg" sort="Guest, Greg" uniqKey="Guest G" first="Greg" last="Guest">Greg Guest</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Division of Behavioral and Biomedical Research, Family Health International</s1>
<s2>North Carolina</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Shattuck, Dominick" sort="Shattuck, Dominick" uniqKey="Shattuck D" first="Dominick" last="Shattuck">Dominick Shattuck</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Division of Behavioral and Biomedical Research, Family Health International</s1>
<s2>North Carolina</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Johnson, Laura" sort="Johnson, Laura" uniqKey="Johnson L" first="Laura" last="Johnson">Laura Johnson</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Division of Behavioral and Biomedical Research, Family Health International</s1>
<s2>North Carolina</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Akumatey, Betty" sort="Akumatey, Betty" uniqKey="Akumatey B" first="Betty" last="Akumatey">Betty Akumatey</name>
<affiliation wicri:level="4"><inist:fA14 i1="02"><s1>Department of Sociology, University of Ghana</s1>
<s2>Legon</s2>
<s3>GHA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Ghana</country>
<placeName><settlement type="city">Accra</settlement>
<settlement type="town">Legon (Ghana)</settlement>
<region type="region">Région du Grand Accra</region>
</placeName>
<orgName type="university">Université du Ghana</orgName>
</affiliation>
</author>
<author><name sortKey="Kekawo Clarke, Edith Essie" sort="Kekawo Clarke, Edith Essie" uniqKey="Kekawo Clarke E" first="Edith Essie" last="Kekawo Clarke">Edith Essie Kekawo Clarke</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Ghana Health Service, Ministry of Health</s1>
<s3>GHA</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Ghana</country>
<wicri:noRegion>Ghana Health Service, Ministry of Health</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chen, Pai Lien" sort="Chen, Pai Lien" uniqKey="Chen P" first="Pai-Lien" last="Chen">Pai-Lien Chen</name>
<affiliation wicri:level="2"><inist:fA14 i1="04"><s1>Division of Biostatistics, Family Health International</s1>
<s2>North Carolina</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Macqueen, Kathleen M" sort="Macqueen, Kathleen M" uniqKey="Macqueen K" first="Kathleen M." last="Macqueen">Kathleen M. Macqueen</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Division of Behavioral and Biomedical Research, Family Health International</s1>
<s2>North Carolina</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Sexually transmitted diseases</title>
<title level="j" type="abbreviated">Sex. transm. dis.</title>
<idno type="ISSN">0148-5717</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Sexually transmitted diseases</title>
<title level="j" type="abbreviated">Sex. transm. dis.</title>
<idno type="ISSN">0148-5717</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>AIDS</term>
<term>Clinical trial</term>
<term>Prevention</term>
<term>Sexual behavior</term>
<term>Sexually transmitted disease</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>SIDA</term>
<term>Maladie sexuellement transmissible</term>
<term>Comportement sexuel</term>
<term>Prévention</term>
<term>Essai clinique</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Maladie sexuellement transmissible</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Background: One of the concerns raised regarding the introduction of any new HIV-prevention measure, such as PrEP, is the potential for risk disinhibition or sexual risk compensation. The oral tenofovir HIV prevention trial has been the subject of international discussion in this regard. Methods: This article maps the changes in sexual risk behavior among women participating in the oral tenofovir HIV prevention trial in Ghana. Content-driven, thematic analysis was carried out on qualitative data obtained from in-depth interviews with study participants. Growth curve analysis was the primary method used to document trends over time in self-reported sexual behavior collected monthly. Results: Overall, the study found that sexual risk behavior did not increase during the trial. Number of sexual partners and rate of unprotected sex acts decreased across the 12-month period of study enrollment. Certain subgroups of women, however, exhibited different growth curves. Data indicate that the HIV prevention counseling associated with the trial was effective. Conclusions: Counseling during the trial was effective. Different types of counseling and messaging may be needed for different subgroups within a population. These findings also have implications for required sample sizes for future HIV prevention trials where seroconversion is the main outcome.</div>
</front>
</TEI>
<affiliations><list><country><li>Ghana</li>
<li>États-Unis</li>
</country>
<region><li>Caroline du Nord</li>
<li>Région du Grand Accra</li>
</region>
<settlement><li>Accra</li>
<li>Legon (Ghana)</li>
</settlement>
<orgName><li>Université du Ghana</li>
</orgName>
</list>
<tree><country name="États-Unis"><region name="Caroline du Nord"><name sortKey="Guest, Greg" sort="Guest, Greg" uniqKey="Guest G" first="Greg" last="Guest">Greg Guest</name>
</region>
<name sortKey="Chen, Pai Lien" sort="Chen, Pai Lien" uniqKey="Chen P" first="Pai-Lien" last="Chen">Pai-Lien Chen</name>
<name sortKey="Johnson, Laura" sort="Johnson, Laura" uniqKey="Johnson L" first="Laura" last="Johnson">Laura Johnson</name>
<name sortKey="Macqueen, Kathleen M" sort="Macqueen, Kathleen M" uniqKey="Macqueen K" first="Kathleen M." last="Macqueen">Kathleen M. Macqueen</name>
<name sortKey="Shattuck, Dominick" sort="Shattuck, Dominick" uniqKey="Shattuck D" first="Dominick" last="Shattuck">Dominick Shattuck</name>
</country>
<country name="Ghana"><region name="Région du Grand Accra"><name sortKey="Akumatey, Betty" sort="Akumatey, Betty" uniqKey="Akumatey B" first="Betty" last="Akumatey">Betty Akumatey</name>
</region>
<name sortKey="Kekawo Clarke, Edith Essie" sort="Kekawo Clarke, Edith Essie" uniqKey="Kekawo Clarke E" first="Edith Essie" last="Kekawo Clarke">Edith Essie Kekawo Clarke</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/SidaGhanaV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C26 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000C26 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    SidaGhanaV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:09-0059294
   |texte=   Changes in Sexual Risk Behavior Among Participants in a PrEP HIV Prevention Trial
}}

This area was generated with Dilib version V0.6.31.
Data generation: Tue Nov 7 18:07:38 2017. Site generation: Tue Mar 5 15:01:57 2024

	Le SIDA au Ghana (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Le SIDA au Ghana (serveur d'exploration)

Changes in Sexual Risk Behavior Among Participants in a PrEP HIV Prevention Trial

Changes in Sexual Risk Behavior Among Participants in a PrEP HIV Prevention Trial

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri